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Systematical comparison reveals distinct brain transcriptomic features in models of depression induced by gut microbiota dysbiosis and chronic stress

2024-03-29

Abstract excerpt

<title>Abstract</title> <p>Major depressive disorder (MDD) is a devastating psychiatric illness caused by various etiologies. Both chronic stress and gut microbiome dysbiosis are implicated in the pathogenesis of MDD. However, limited research was undertaken to delineate the distinct effects of these two pathogenic factors on the brain transcriptome. We generated and compared transcriptomic features of anterior c...

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Literature Corpus work
992e4a51-9e2b-5fbc-b7fd-4c0aa6d28489
DOI
10.21203/rs.3.rs-4134877/v1
Open publication

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Systematical comparison reveals distinct brain transcriptomic features in models of depression induced by gut microbiota dysbiosis and chronic stressDOI 10.21203/rs.3.rs-4134877/v1
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