Prediction of zoonotic virus-host transmissibility using comparative airway organoids

Abstract excerpt

<h4> Abstract </h4> The emergence of new pandemic zoonotic diseases is accelerating. However, current approaches to control after outbreaks often allow the epidemic or pandemic spread of new zoonotic diseases, exemplified by the case of COVID-19. Prediction of zoonotic transmissibility will help minimize the outbreaks and socioeconomic damage. Here, we established highly efficient comparative airway organoids wi...

Topics

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• Animal Disease Management and Epidemiology
• Bat Biology and Ecology Studies
• Influenza Virus Research Studies
• Respiratory viral infections research
• Single-cell and spatial transcriptomics
• Viral gastroenteritis research and epidemiology
• Viral Infections and Vectors
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

0cd28a90-4ae3-5ae3-9dc3-ee162abd14df

DOI

10.1101/2025.09.12.675569