Article

Antiviral response mechanisms in a Jamaican Fruit Bat intestinal organoid model of SARS-CoV-2 infection

2022-12-12

Abstract excerpt

<title>Abstract</title> <p>Bats are natural reservoirs for several zoonotic viruses, potentially due to an enhanced capacity to control viral infection. However, the mechanisms of antiviral responses in bats are poorly defined. Here we established a Jamaican fruit bat (JFB) intestinal organoid model of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. JFB organoids were susceptible to SARS-C...

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Literature Corpus work: c423ebff-8153-5b6f-bd4e-df5d05f97978
DOI: 10.21203/rs.3.rs-2340919/v1

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