Article

Overlapping and Distinct Functions of an Extended Repertoire of KRAS Mutations

2023-05-08

Abstract excerpt

<title>Abstract</title><p>The challenge of interpreting novel genetic variations in genomics is widespread. Previous studies have shown the role of KRAS mutations in heritable and somatic conditions, but more genetic variants have been observed than have been characterized. This study compares a broad genomic landscape of 25 KRAS mutations at three cellular checkpoint levels: ERK and AKT signaling, early cell-intr...

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Literature Corpus work: 990a69c9-679f-5ac1-a8ae-5089cd18b8ab
DOI: 10.21203/rs.3.rs-2883088/v1

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