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Lipid Metabolism Reprogramming Is Associated with Trastuzumab Resistance in ERBB2+ Breast Cancer Cell Lines

2023-04-03

Abstract excerpt

The antibody Trastuzumab (Tz) targeting ERBB2 has improved the prognosis of patients with breast cancer (BCa) that overexpress this receptor. Resistance to Tz negatively impacts prognosis. Several mechanisms have been reported to cause Tz resistance. The objective of this study was to identify common mechanisms in in vitro models of acquired BCa Tz resistance. In particular, we used three widely available ERBB2+ B...

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Literature Corpus work
98ea5503-383b-5e64-b38e-3511e9154b1e
DOI
10.20944/preprints202304.0002.v1
Open publication

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Lipid Metabolism Reprogramming Is Associated with Trastuzumab Resistance in ERBB2+ Breast Cancer Cell LinesDOI 10.20944/preprints202304.0002.v1
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