Article

Association of tamoxifen resistance and lipid reprogramming in breast cancer

2018-03-05

Abstract excerpt

<h4>Background</h4> Tamoxifen treatment of estrogen receptor (ER)-positive breast cancer reduces mortality by 31%. However, over half of advanced ER-positive breast cancers are intrinsically resistant to tamoxifen and about 40% will acquire the resistance during the treatment. <h4>Methods</h4> In order to explore mechanisms underlying endocrine therapy resistance in breast cancer and to identify new therapeutic...

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Literature Corpus work: b6bb7e79-cb11-5f83-b9c9-425f9b7174c7
DOI: 10.1101/276618

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