Article

Development of a Matrix-Matched Calibration Curve for Multi-Site Quantification of Neu5Gc-Bearing N-Glycans

2026-07-15

Abstract excerpt

N -glycolylneuraminic acid (Neu5Gc) has been repeatedly associated with human cancer, but reliable detection has remained elusive, generating controversy regarding its presence in human samples. To address this, matrix-matched calibration curves, which have been pioneered in proteomics and metabolomics for assessing changes in complex mixtures, were measured of released N -glycans at four orders of magnitude dyna...

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Literature Corpus work: 98c0053a-6de9-57e8-8225-ebd504ec621b
DOI: 10.64898/2026.07.14.738351

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