Development and application of GlycanDIA workflow for glycomic analysis

Abstract excerpt

Glycans modify protein, lipid, and even RNA molecules to form the regulatory outer coat on cells called the glycocalyx. The changes in glycosylation have been linked to the initiation and progression of many diseases. Thus, while the significance of glycosylation is well established, a lack of accessible methods to characterize glycans has hindered the ability to understand their biological functions. Mass spectro...

Topics

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• Congenital Disorders of Glycosylation
• Glycosylation
• Glycosylation and Glycoproteins Research
• Mass Spectrometry
• Mutation
• Peptidase Inhibition and Analysis
• Polysaccharides
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

c0ec7070-87f4-5c35-b6cb-cdcce36fdf6c

DOI

10.1101/2024.03.12.584702