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Article

Aging-Relevant Human Basal Forebrain Cholinergic Neurons as a Cell Model for Alzheimer’s Disease

2020-05-22

Abstract excerpt

<title>Abstract</title> <p>Background : Alzheimer’s disease (AD) is an adult-onset mental disorder with aging as a major risk factor. Early and progressive degeneration of basal forebrain cholinergic neurons (BFCNs) contributes substantially to cognitive impairments of AD. An aging-relevant cell model of BFCNs will critically help understand AD and identify potential therapeutics. Recent studies demonstrate that...

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Literature Corpus work
98ad6c4d-459d-5c81-beb1-de4a3d221d77
DOI
10.21203/rs.3.rs-29101/v1
Open publication

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