Article

Minimally invasive determination of PDAC subtype and therapy-induced subtype switch by means of circulating cell-free RNA

2024-01-09

Abstract excerpt

<title>Abstract</title><p>Background Pancreatic ductal adenocarcinoma (PDAC) comprises two clinically relevant subtypes. Currently, determining the tumor subtype relies on tissue biopsies. Unfortunately, these biopsies are spatially biased, highly invasive, difficult to obtain, and unsuitable for monitoring tumor dynamics. Methods We employed whole transcriptome sequencing (WTS) on circulating cell-free (cf) RNA i...

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Literature Corpus work: 989d5ca2-6231-5e54-9756-c322d1ea5d18
DOI: 10.21203/rs.3.rs-3688314/v1

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