Article
Evidence for molecular subtyping in pancreatic ductal adenocarcinoma: a systematic review.
HPB : the official journal of the International Hepato Pancreato Biliary Association - 1 May 2024
Robertson Francis P, Cameron Andrew, Spiers Harry V M, Joseph Nejo, Taylor Ellie, Ratnayake Bathiya, Jamieson Nigel B, Pandanaboyana Sanjay
Abstract excerpt
BACKGROUND: Pancreatic Ductal Adenocarcinoma (PDAC) patients exhibit varied responses to multimodal therapy. RNA gene sequencing has unravelled distinct tumour biology subtypes, forming the focus of this review exploring its impact on survival outcomes. METHODS: A systematic search across PubMed, Medline, Embase, and CINAHL databases targeted studies assessing long-term overall and disease-free survival in PDAC...
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