Article

Generation of a recombinant GST-Tau antigen for indirect ELISA in evaluating Alzheimer’s disease vaccines

2025-09-20

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease is a progressive neurodegenerative disorder. Immunotherapy targeting Aβ and Tau proteins is a promising strategy, and accurate detection of anti-Aβ or anti-Tau antibodies is key to evaluating vaccine efficacy. Indirect ELISA is a sensitive method requiring high-quality coating antigens. <h4>Methodology</h4> A recombinant Tau antigen fused to glutathione S-transferase (GST)...

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Literature Corpus work: 9854aa0d-6c03-5198-b8c6-79e724e5c5a6
DOI: 10.1101/2025.09.18.676867

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