Article

Interactions of SARS-CoV-2 protein E with cell junctions and polarity PDZ-containing proteins

2021-12-06

Abstract excerpt

The C-terminus of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein E contains a PBM (PDZ binding motif) targeting PDZ (PSD-95/Dlg/ZO-1) domains identical to the PBM of SARS-CoV. The latter is involved in the pathogenicity of the virus. Recently, we identified ten human PDZ-containing proteins showing significant interactions with SARS-CoV-2 protein E PBM. We selected several of them involve...

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Literature Corpus work: 984b49e1-49a3-5ae7-b476-fa19a7dc727f
DOI: 10.1101/2021.12.04.471219

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