Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS‐CoV‐2 spike protein harnesses SNX27‐mediated endocytic recycling pathway

8 Oct 2021

Abstract excerpt

SARS-CoV-2 is an enveloped positive-sense RNA virus that depends on host factors for all stages of its life. Membrane receptor ACE2 is a well-established factor for SARS-CoV-2 docking. In addition to ACE2, whole-genome genetic screens have identified additional proteins, such as endosomal trafficking regulators SNX27 and retromer, as key host factors required for SARS-CoV-2 infection. However, it is poorly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral Infections and Outbreaks Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34909756
DOI: 10.1002/mco2.92

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS‐CoV‐2 spike protein harnesses SNX27‐mediated endocytic recycling pathwayPMID 34909756Read ↗

Interaction network of SARS-CoV-2 with host receptome through spike proteinSemantic proximity Read ↗

An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking.Semantic proximity Read ↗

The biogenesis of SARS-CoV-2 spike glycoprotein: multiple targets for host-directed antiviral therapySemantic proximity Read ↗

Structure, Function, and Evolution of Coronavirus Spike ProteinsSemantic proximity Read ↗

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.Semantic proximity Read ↗

ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egressSemantic proximity Read ↗

Ribophorin-1 Governs Spike Abundance of Highly Pathogenic Coronaviruses by ER-associated degradationSemantic proximity Read ↗

Coronavirus entry: how we arrived at SARS-CoV-2Semantic proximity Read ↗

Spike glycoproteins: Their significance for corona viruses and receptor binding activities for pathogenesis and viral survivalSemantic proximity Read ↗

A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entrySemantic proximity Read ↗

SARS-CoV-2 harnesses host translational shutoff and autophagy to optimize virus yields: The role of the envelope (E) proteinSemantic proximity Read ↗

Deletion of the Envelope gene attenuates SARS-CoV-2 infection by altered Spike localization and increased cell-to-cell transmissionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.