Article

The SARS-CoV-2 envelope PDZ Binding Motif acts as a virulence factor disrupting host’s epithelial cell-cell junctions

2024-12-10

Abstract excerpt

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus responsible for the COVID-19 pandemic, has significantly impacted global health, emphasizing the need to understand its pathogenicity and virulence mechanisms. SARS-CoV-2 disrupts the alveolar epithelial barrier and exacerbates airway inflammation, leading to acute respiratory failure, but the molecular details remain unclear. Additionally, SA...

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Literature Corpus work: 2617697f-3129-585f-be59-b9d4cc6575e4
DOI: 10.1101/2024.12.10.627528

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