Article

Enhanced binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis

2020-05-22

Abstract excerpt

<h4>Background: </h4> The Envelope (E) protein of SARS-CoV-2 is the most enigmatic protein among the four structural ones on the viral genome. Most of the current knowledge on the E protein is based on the direct comparison to the SARS E protein, initially mistakenly undervalued and subsequently proved to be a key factor in the ER-Golgi localization and in tight junction disruption. <h4>Methods: </h4>: We compared...

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Literature Corpus work: efae42a4-a538-5319-bd73-925cf5b6c0eb
DOI: 10.21203/rs.3.rs-30903/v1

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