Article

Host PDZ-containing proteins targeted by SARS-Cov-2

2021-02-01

Abstract excerpt

Small linear motif targeting protein interacting domains called PDZ have been identified at the C-terminus of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins E, 3a, and N. Using a high-throughput approach of affinity-profiling against the full human PDZome, we identified sixteen human PDZ binders of SARS-CoV-2 proteins E, 3A and N showing significant interactions with dissociation constan...

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Literature Corpus work: b277924d-7821-5d38-9344-d8fda05abac5
DOI: 10.1101/2021.02.01.429176

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