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Diversity in host clone performance within a <scp>C</scp> hinese hamster ovary cell line

28 Apr 2015

Abstract excerpt

Much effort has been expended to improve the capabilities of individual Chinese hamster ovary (CHO) host cell lines to synthesize recombinant therapeutic proteins (rPs). However, given the increasing variety in rP molecular types and formats it may be advantageous to employ a toolbox of CHO host cell lines in biomanufacturing. Such a toolbox would contain a panel of hosts with specific capabilities to synthesize...

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PMID: 25918883
DOI: 10.1002/btpr.2097

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