Article
ERRgamma regulates cardiac, gastric, and renal potassium homeostasis.
Molecular endocrinology (Baltimore, Md.) - 1 Feb 2010
Alaynick William A, Way James M, Wilson Stephanie A, Benson William G, Pei Liming, Downes Michael, Yu Ruth, Jonker Johan W, Holt Jason A, Rajpal Deepak K, Li Hao, Stuart Joan, McPherson Ruth, Remlinger Katja S, Chang Ching-Yi, McDonnell Donald P, Evans Ronald M, Billin Andrew N
Abstract excerpt
Energy production by oxidative metabolism in kidney, stomach, and heart, is primarily expended in establishing ion gradients to drive renal electrolyte homeostasis, gastric acid secretion, and cardiac muscle contraction, respectively. In addition to orchestrating transcriptional control of oxidative metabolism, the orphan nuclear receptor, estrogen-related receptor gamma (ERRgamma), coordinates expression of...
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