Article

Tissue-specific Gene Expression Prediction Associates Vitiligo with SUOX through an Active Enhancer

2018-06-02

Abstract excerpt

Vitiligo is an autoimmune disease featuring destruction of melanocytes, which results in patchy depigemtation of skin and hair; two vitiligo GWAS studies identified multiple significant associations, including SNPs in 12q13.2 region. But one study ascribed the association to IKZF4 because it encodes a regulator of T cell activation and is associated with two autoimmune diseases; while the other study ascribed the...

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Literature Corpus work: 97f991a2-a44a-5c79-bd28-a79df5232029
DOI: 10.1101/337196

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