Article
A comprehensive association analysis confirms ZMIZ1 to be a susceptibility gene for vitiligo in Chinese population.
Journal of medical genetics - 1 May 2014
Sun Yonghu, Zuo Xianbo, Zheng Xiaodong, Zhou Fusheng, Liang Bo, Liu Hong, Chang Ruixue, Gao Jinping, Sheng Yujun, Cui Hongzhou, Wang Wenjun, Andiappan Anand Kumar, Rotzschke Olaf, Yang Sen, Sun Liangdan, Zhang Furen, Zhang Xuejun, Ren Yunqing, Liu Jianjun
Abstract excerpt
BACKGROUND: ZMIZ1 has been shown to be associated with multiple autoimmune diseases and play a role in the development of melanocyte. The association of ZMIZ1 with vitiligo was also suggested, but the evidence did not reach genome-wide significance and has not been confirmed by independent studies. METHODS: A fine mapping analysis of the ZMIZ1 locus was carried out in the dataset of 1117 vitiligo patients and...
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