Article

Toxicity of immunosuppressive drugs on human fetal kidney development; a study using organotypic culture

2026-07-27

Abstract excerpt

<title>Abstract</title> <p>Immunosuppressants, including calcineurin inhibitors and corticosteroids, are used during pregnancy to treat autoimmune diseases and prevent transplant rejection. Their use requires balancing maternal benefits against potential fetal toxicity, as calcineurin inhibitors are nephrotoxic in adults and cross the placenta. This study investigated whether immunosuppressants induce toxicity or...

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Literature Corpus work: 97f0119e-4515-5f4d-a2ae-de8e7f24ba09
DOI: 10.21203/rs.3.rs-10280476/v1

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