Article
Toward better assessments of developmental toxicity using stem cell‐based in vitro embryogenesis models
31 Jan 2022
Abstract excerpt
In the past few decades, pluripotent stem cells have been explored as nonanimal alternatives to assess the developmental toxicity of chemicals. To date, numerous versions of stem cell-based assays have been reported that are allegedly effective. Nonetheless, none of the assays has become the gold standard in developmental toxicity assessment. Why? This article discusses several issues in the hope of facilitating...
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