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Species Differences in Renal Development and Associated Developmental Nephrotoxicity

2 Aug 2017

Abstract excerpt

The developing kidney is sensitive to both morphological and functional disturbances during the gestational and postnatal phases of growth and differentiation. Exposure to drugs or chemicals during these critical windows of renal development can result in aplasia, dysplasia, polycystic kidney disease, hydronephrosis, or other features characteristic of nephrotoxicity, including tubule dilation, necrosis, or...

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PMID: 28766875
DOI: 10.1002/bdr2.1088

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