Article

Immunosuppression with Cyclosporine versus Tacrolimus shows distinctive nephrotoxicity profiles within renal compartments

2023-04-06

Abstract excerpt

Calcineurin inhibitors (CNI) are the backbone for immunosuppression after solid organ transplantation. Although successful in preventing kidney transplant rejection, their nephrotoxic side effects notoriously contribute to allograft injury despite attempts to optimize their application, often with additional medications. Complex renal parenchymal damage occurs for cyclosporine A (CsA) as well as for the currently...

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Literature Corpus work: be31861b-d38a-5c32-95a7-635ff5ff15c5
DOI: 10.1101/2023.04.05.535688

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