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Article

Use of Organ Culture to Study the Human Fetal Testis Development: Effect of Retinoic Acid

18 Apr 2006

Abstract excerpt

CONTEXT: In human, the chronology of the testicular development has been extensively studied, but the factors implicated in the onset and the regulation of gametogenesis and steroidogenesis remain hardly known. OBJECTIVES: To identify these factors, we developed an organ culture system for human fetal testes recovered during the first trimester (6-12 wk) of gestation. We first aimed at investigating the...

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PMID: 16621909
DOI: 10.1210/jc.2005-2113

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