Article

A computational panel of pathological RAS mutants with implications for personalized medicine and genetic medicine

2017-06-21

Abstract excerpt

<h4>ABSTRACT</h4> The RAS proteins (KRAS, NRAS, and HRAS) play important roles in multiple diseases. This includes many types of cancer and the developmental syndromes collectively referred to as the RASopathies. There are many different RAS mutants that are found to drive these diseases. Mutant-to-mutant differences pose a challenge for personalized medicine. To investigate this problem, we extend our previously...

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Literature Corpus work: 97d3ad32-3c76-5276-bef0-7998804b6490
DOI: 10.1101/153726

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