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Article

The Ins and Outs of RAS Effector Complexes.

Biomolecules - 7 Feb 2021

Kiel Christina, Matallanas David, Kolch Walter

Abstract excerpt

RAS oncogenes are among the most commonly mutated proteins in human cancers. They regulate a wide range of effector pathways that control cell proliferation, survival, differentiation, migration and metabolic status. Including aberrations in these pathways, RAS-dependent signaling is altered in more than half of human cancers. Targeting mutant RAS proteins and their downstream oncogenic signaling pathways has...

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Identifiers

PMID: 33562401
DOI: 10.3390/biom11020236
PMCID: PMC7915224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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