Back to search

Article

A versatile, marker-free platform for life cycle-wide imaging in <i>Plasmodium falciparum</i> via integration of an exogenous gene cassette into a conserved intergenic locus

2026-01-21

Abstract excerpt

<h4>ABSTRACT</h4> The development of a transgenic Plasmodium falciparum line that exhibits robust fluorescence throughout its life cycle in cultured cells and mosquito hosts is valuable for live imaging, tissue localization studies, and quantitative evaluations of parasite infectivity. In this study, we utilized Plasmodium -optimized genome editing to integrate an mCherry expression cassette into a specific int...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
97b42975-fea1-55c3-8952-d57e01d81b9c
DOI
10.64898/2026.01.21.700814
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A versatile, marker-free platform for life cycle-wide imaging in <i>Plasmodium falciparum</i> via integration of an exogenous gene cassette into a conserved intergenic locusDOI 10.64898/2026.01.21.700814
Generation of Transgenic Human Malaria Parasites With Strong Fluorescence in the Transmission StagesSemantic proximity
Generation of a <i>Plasmodium falciparum</i> reporter line for studies of parasite biology throughout the life cycleSemantic proximity
Flow cytometry-based evaluation of hepatic infection by non-fluorescent <i>Plasmodium</i> parasitesSemantic proximity
A transgenic Plasmodium falciparum NF54 strain that expresses GFP–luciferase throughout the parasite life cycleSemantic proximity
Development of the endoplasmic reticulum, mitochondrion and apicoplast during the asexual life cycle of <i>Plasmodium falciparum</i>Semantic proximity
Rapid Generation of Marker-Free P. falciparum Fluorescent Reporter Lines Using Modified CRISPR/Cas9 Constructs and Selection Protocol.Semantic proximity
Global gene expression of human malaria parasite liver stages throughout intrahepatocytic developmentSemantic proximity
Fluorescent <i>Plasmodium berghei</i> sporozoites and pre-erythrocytic stages: a new tool to study mosquito and mammalian host interactions with malaria parasitesSemantic proximity
CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission researchSemantic proximity
Ribozyme-Mediated, Multiplex CRISPR Gene Editing and CRISPRi in <i>Plasmodium yoelii</i>Semantic proximity
Transgenic pyrimethamine-resistant <i>P. falciparum</i> reveals transmission blocking potency of P218, a novel antifolateSemantic proximity
Capturing <i>in vivo</i> RNA transcriptional dynamics from the malaria parasite <i>P. falciparum</i>Semantic proximity
Select a neighboring publication to make it the new centre.