Development of an anti-Pfs230 monoclonal antibody as a Plasmodium falciparum gametocyte blocker

Abstract excerpt

Vector control is a crucial strategy for malaria elimination by preventing infection and reducing disease transmission. Most gains have been achieved through insecticide-treated nets (ITNs) and indoor residual spraying (IRS), but the emergence of insecticide resistance among Anopheles mosquitoes calls for new tools to be applied. Here, we present the development of a highly effective murine monoclonal antibody, ta...

Topics

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• Complement system in diseases
• Insect Resistance and Genetics
• Insect symbiosis and bacterial influences
• Invertebrate Immune Response Mechanisms
• Malaria Research and Control
• Mosquito-borne diseases and control
• Trypanosoma species research and implications
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

974f7422-1bb8-5563-b3fd-60ba050a50ee

DOI

10.21203/rs.3.rs-3757253/v1