Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Monoclonal antibodies block transmission of genetically diverse Plasmodium falciparum strains to mosquitoes

12 Aug 2021

Abstract excerpt

Abstract Malaria parasite transmission to mosquitoes relies on the uptake of sexual stage parasites during a blood meal and subsequent formation of oocysts on the mosquito midgut wall. Transmission-blocking vaccines (TBVs) and monoclonal antibodies (mAbs) target sexual stage antigens to interrupt human-to-mosquito transmission and may form important tools for malaria elimination. Although most epitopes of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect symbiosis and bacterial influences
Share to Invertebrate Immune Response Mechanisms
Share to Malaria Research and Control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34385463
DOI: 10.1038/s41541-021-00366-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Monoclonal antibodies block transmission of genetically diverse Plasmodium falciparum strains to mosquitoesPMID 34385463Read ↗

Transmission-reducing and -enhancing monoclonal antibodies against Plasmodium vivax gamete surface protein Pvs48/45Semantic proximity Read ↗

Pfs230 Domain 7 is targeted by a potent malaria transmission-blocking monoclonal antibodySemantic proximity Read ↗

A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametesSemantic proximity Read ↗

Pooled Amplicon Deep Sequencing of Candidate Plasmodium falciparum Transmission-Blocking Vaccine Antigens.Semantic proximity Read ↗

Heterologous Expression and Evaluation of Novel Plasmodium falciparum Transmission Blocking Vaccine CandidatesSemantic proximity Read ↗

Diversity and selection analyses identify transmission-blocking antigens as the optimal vaccine candidates in<i>Plasmodium falciparum</i>Semantic proximity Read ↗

A high affinity human monoclonal antibody against Pfs230 binds multiple parasite stages and blocks oocyst formation in mosquitoesSemantic proximity Read ↗

Genetic diversity of transmission-blocking vaccine candidate Pvs48/45 in Plasmodium vivax populations in China.Semantic proximity Read ↗

Diversity and selection analyses identify transmission-blocking antigens as the optimal vaccine candidates in Plasmodium falciparum.Semantic proximity Read ↗

Pfs48/45 nanobodies block <i>Plasmodium falciparum</i> transmissionSemantic proximity Read ↗

Malaria transmission‐blocking antigen, Pfs230, mediates human red blood cell binding to exflagellating male parasites and oocyst productionSemantic proximity Read ↗

Minimal variation in the transmission-blocking vaccine candidate Pfs48/45 of the human malaria parasite Plasmodium falciparum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.