Article

Antioxidant defenses of <i>Francisella tularensis</i> perturb Aim2 Inflammasome Activation

2026-04-11

Abstract excerpt

<h4>ABSTRACT</h4> Francisella tularensis is a Gram-negative bacterium that causes tularemia, a fatal zoonotic disease. F. tularensis has been used in the bioweapon programs of several countries. Its potential use as a bioterrorism agent led the CDC to classify F. tularensis as a Tier 1 Select Agent. The cytosolic sensor absent in melanoma 2 (Aim2) detects double-stranded DNA in the cytosol of infected cells and...

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Literature Corpus work: 974f463e-2213-5c7a-9ead-00d105de432e
DOI: 10.64898/2026.04.09.717616

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