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Article

Repression of inflammasome by Francisella tularensis during early stages of infection.

The Journal of biological chemistry - 16 Aug 2013

Dotson Rachel J, Rabadi Seham M, Westcott Elizabeth L, Bradley Stephen, Catlett Sally V, Banik Sukalyani, Harton Jonathan A, Bakshi Chandra Shekhar, Malik Meenakshi

Abstract excerpt

Francisella tularensis is an important human pathogen responsible for causing tularemia. F. tularensis has long been developed as a biological weapon and is now classified as a category A agent by the Centers for Disease Control because of its possible use as a bioterror agent. F. tularensis represses inflammasome; a cytosolic multi-protein complex that activates caspase-1 to produce proinflammatory cytokines...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23821549
DOI: 10.1074/jbc.M113.490086
PMCID: PMC3745331

Genes

AIM2
NLRP3
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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