Article

Microvascular preservation and cardiomyocyte hyperplasia underlie adaptive right ventricular development in congenital heart disease-associated pulmonary arterial hypertension

2024-12-09

Abstract excerpt

<h4> Abstract </h4> <h4>Background</h4> Right ventricular (RV) failure is the primary cause of death among patients with pulmonary arterial hypertension (PAH). Patients with congenital heart disease- associated PAH (CHD-PAH) demonstrate improved outcomes compared to patients with other forms of PAH, which is related to the maintenance of an adaptively hypertrophied RV. In an ovine model of CHD-PAH, we aimed to...

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Literature Corpus work: 971fc921-dc6f-5345-bf18-ba7e7654aebe
DOI: 10.1101/2024.12.04.626551

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