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Article

Bimodal right ventricular dysfunction after postnatal hyperoxia exposure: implications for the preterm heart.

American journal of physiology. Heart and circulatory physiology - 1 Dec 2019

Kumari Santosh, Braun Rudolf K, Tetri Laura H, Barton Gregory P, Hacker Timothy A, Goss Kara N

Abstract excerpt

Rats exposed to postnatal hyperoxia develop right ventricular (RV) dysfunction, mild pulmonary hypertension, and dysregulated cardiac mitochondrial biogenesis when aged to one year, with the degree of cardiac dysfunction and pulmonary hypertension similar to that previously described in young adults born preterm. Here, we sought to understand the impact of postnatal hyperoxia exposure on RV hemodynamic and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31702968
DOI: 10.1152/ajpheart.00383.2019
PMCID: PMC6962619

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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