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Article

Molecular Signature of a Right Heart Failure Program in Chronic Severe Pulmonary Hypertension

1 Jul 2011

Abstract excerpt

Right heart failure is the cause of death of most patients with severe pulmonary arterial hypertensive (PAH) disorders, yet little is known about the cellular and molecular causes of right ventricular failure (RVF). We first showed a differential gene expression pattern between normal rat right and left ventricles, and postulated the existence of a molecular right heart failure program that distinguishes RVF from...

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PMID: 21719795
DOI: 10.1165/rcmb.2010-0412oc

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