Article

A common gene signature of the right ventricle in failing rat and human hearts

2023-05-18

Abstract excerpt

<h4>Summary</h4> The molecular mechanisms of progressive right heart failure are incompletely understood. We systematically compared rat models of pulmonary artery or aortic banding to identify the transcriptomic changes that occur over months in the failing right versus left ventricle. Detailed bioinformatics analyses of 181 RNAseq datasets from cardiomyocytes or whole heart samples from these models, led to the...

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Literature Corpus work: ce837738-5a27-5c87-97a4-69c0213bf4e0
DOI: 10.1101/2023.05.16.540913

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