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Increased Vulnerability against Ferroptosis in FUS‐ ALS

2024-02-29

Abstract excerpt

Ferroptosis, a regulated form of cell death characterized by iron-dependent lipid peroxide accumulation, plays a pivotal role in various pathological conditions, including neurodegenerative diseases. While reasonable evidence for ferroptosis exist e.g. in Parkinson’s disease or Alzheimer’s disease, there are only few reports on amyotrophic lateral sclerosis (ALS), a fast progressive and incurable neurodegenerative...

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Literature Corpus work
970c4b89-c810-5e42-be03-ed6018705e45
DOI
10.20944/preprints202402.1762.v1
Open publication

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