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β-Amyloid and Glutathione Dysregulation Cooperatively Drive Lipid Peroxidation and Ferroptosis in Neuron-Like Cells

2026-04-17

Abstract excerpt

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by β-amyloid (Aβ) accumulation and oxidative stress, with aging being its greatest risk factor. Age-related decline in antioxidant defenses, particularly glutathione (GSH), may increase neuronal vulnerability to Aβ-mediated toxicity; however, the mechanisms linking redox dysregulation to neuronal death remain incompletely understood...

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Literature Corpus work
abc6ba62-3644-5222-ab0a-e0e45fcc6ce4
DOI
10.64898/2026.04.15.718809
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β-Amyloid and Glutathione Dysregulation Cooperatively Drive Lipid Peroxidation and Ferroptosis in Neuron-Like CellsDOI 10.64898/2026.04.15.718809
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