Article

A new sensitive and robust next-generation sequencing platform for HIV-1 drug resistance mutations testing

2021-07-19

Abstract excerpt

Next-generation sequencing (NGS) is a trending new platform which allows cheap, quantitative, high-throughput, parallel sequencing for minority variants with frequencies less than 20% of the HIV-1 quasi-species. In clinical setting, these advantages are crucial for choosing antiretroviral drugs with low genetic barriers and will potentially benefit treatment outcomes. In this investigation, we implemented the Boxi...

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Literature Corpus work: 96fbc2bd-ddb6-5900-a501-0750bc82e4ac
DOI: 10.1101/2021.07.13.21260248

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