Article
Evaluation of Vela Diagnostics HIV-1 genotyping assay on an automated next generation sequencing platform.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 2020
May Shoshanna, Adamska Ewelina, Tang Julian
Abstract excerpt
BACKGROUND: Antiretroviral drug resistance testing is an integral part of the management of patients infected with HIV. The traditional Sanger sequencing method is capable of detecting drug resistant mutations (DRMs) that make up at least 10-15% of the viral quasispecies population. Newer next generation sequencing technologies have a greater sensitivity for the detection of minority variant DRMs down to around...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
