Article

Protectin D1/GPR37 signaling enhances macrophage-dependent efferocytosis to attenuate experimental abdominal aortic aneurysm formation

2025-10-21

Abstract excerpt

<h4>ABSTRACT</h4> Abdominal aortic aneurysms (AAAs) are chronic inflammatory vascular disorders characterized by progressive aortic dilation and destruction of the vascular wall, often culminating in rupture. Current management is limited to surgical repair, with no approved targeted pharmacologic therapies. In this study, we investigated the immunomodulatory role of Protectin D1 (PD1), a specialized pro-resolvin...

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Literature Corpus work: 405b12b1-a59c-5d2a-8a2b-bfe88e40ff91
DOI: 10.1101/2025.10.20.683538

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