Article

Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells

2018-05-02

Abstract excerpt

<h4>Background: </h4> : Viral oncogenes and mutated proto-oncogenes are potent drivers of cancer malignancy. Downstream of the oncogenic trigger are alterations in protein properties that give rise to cellular transformation and the acquisition of malignant cellular phenotypes. Developments in mass spectrometry enable large-scale, multidimensional characterisation of proteomes. Such techniques could provide an unp...

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Literature Corpus work: 96dd56d3-66f2-5d33-bc0c-b95bd8374588
DOI: 10.12688/wellcomeopenres.14392.1

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