Back to search

Article

Prognostic Impact of LAG-3 Expression in Early Breast Cancer

2022-09-06

Abstract excerpt

<h4>Background: </h4> Monoclonal antibodies against PD-1 or PD-L1 are established in clinical practice for the treatment of both early and advanced/metastatic triple-negative breast cancer. Beyond the established immune checkpoints (ICPs) (PD-1 and CTLA-4) additional ICPs such as lymphocyte activation gene-3 (LAG-3) are subject of current research. In the present retrospective gene ex-pression analysis, we evaluat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
96c7288a-168c-5969-ad0a-3ed4028bf228
DOI
10.20944/preprints202209.0080.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Prognostic Impact of LAG-3 Expression in Early Breast CancerDOI 10.20944/preprints202209.0080.v1
Molecular and Clinical Characterization of LAG3 in Breast Cancer Through 2994 SamplesSemantic proximity
Lymphocyte-Activation Gene-3 Expression and Prognostic Value in Neoadjuvant-Treated Triple-Negative Breast CancerSemantic proximity
Gene of the month: lymphocyte-activation gene 3 (LAG-3)Semantic proximity
Lymphocyte-activation gene 3 in cancer immunotherapy: function, prognostic biomarker and therapeutic potentialsSemantic proximity
Understanding LAG-3 SignalingSemantic proximity
An immune stratification reveals a subset of PD-1/LAG-3 double-positive triple-negative breast cancers.Semantic proximity
LAG ‐3 transcriptomic expression patterns across malignancies: Implications for precision immunotherapeuticsSemantic proximity
LAG-3: from molecular functions to clinical applicationsSemantic proximity
Pan-cancer and single-cell analysis reveal dual roles of lymphocyte activation gene-3 (LAG3) in cancer immunity and prognosis.Semantic proximity
High expression of lymphocyte-activation gene 3 (LAG3) in chronic lymphocytic leukemia cells is associated with unmutated immunoglobulin variable heavy chain region (IGHV) gene and reduced treatment-free survival.Semantic proximity
Expression and clinical significance of LAG-3, FGL1, PD-L1 and CD8+T cells in hepatocellular carcinoma using Multiplex Quantitative AnalysisSemantic proximity
Integrative analysis identified the key role of LAG3 in T cell exhaustion in gliomaSemantic proximity
Select a neighboring publication to make it the new centre.