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THE TAO OF STEM CELLS IN THE GERMLINE

1 Dec 1997

Abstract excerpt

Germline stem cells (GSCs) are the self-renewing population of germ cells that serve as the source for gametogenesis. GSCs exist in diverse forms, from those that undergo strict self-renewing asymmetric divisions in Drosophila to those that maintain their population by balancing between mitosis and differentiation in Caenorhabditis elegans. Most vertebrate spermatogonial GSCs appear to adopt an intermediate...

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PMID: 9442904
DOI: 10.1146/annurev.genet.31.1.455

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