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Death-associated protein kinase 3 (DAPK3) contributes to intestinal epithelial wound healing and the resolution of experimental colitis in mice

2021-12-03

Abstract excerpt

<h4>ABSTRACT</h4> Various signaling molecules affecting epithelial restitution and wound healing are dysregulated in ulcerative colitis. Recent evidence demonstrates the necessity of Hippo-YAP/TAZ signaling, interceded by cytoskeletal remodeling, for intestinal regeneration. Death-associated protein kinase 3 (DAPK3) is a regulator of actin cytoskeleton reorganization that controls proliferation and apoptosis. Pha...

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Literature Corpus work
969f08e5-c30b-580b-8e7c-d4c7f655e335
DOI
10.1101/2021.12.03.471118
Open publication

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Death-associated protein kinase 3 (DAPK3) contributes to intestinal epithelial wound healing and the resolution of experimental colitis in miceDOI 10.1101/2021.12.03.471118
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