Article

Nodakenin ameliorated TNBS-induced experimental colitis in mice by inhibiting intestinal epithelial cell pyroptosis

2023-01-18

Abstract excerpt

<h4>Background and Aims: </h4> Pyroptosis of intestinal epithelial cells is associated with intestinal barrier dysfunction and the intestinal inflammatory symptoms of Crohn's disease (CD). The natural plant monomer, nodakenin (Nod), inhibits NOD-like receptor protein 3 (NLRP3) expression, and this study aimed to evaluate its effect on CD-like colitis, as well as possible mechanisms. Methods Using TNBS intervention...

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Literature Corpus work: 87f6027a-7667-5885-a0f9-77274b0a5959
DOI: 10.21203/rs.3.rs-2482997/v1

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