Article

Whole genome sequencing of nearly isogeneic WMI and WLI inbred rats identifies genes potentially involved in depression

2020-12-06

Abstract excerpt

<h4>Background</h4> The WMI and WLI inbred rat substrains were generated from the stress-prone, and not yet fully inbred, Wistar Kyoto (WKY) strain using bi-directional selection for immobility in the forced swim test followed by over 38 generations of inbreeding. Despite the low level of genetic diversity among WKY progenitors, the WMI substrain is more vulnerable to stress relative to its WLI control substrain....

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Literature Corpus work: 96826b25-6d26-53e3-ba7c-f9573f03054d
DOI: 10.1101/2020.12.04.411769

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