Article
Sex differences in the genetic architecture of depression.
Scientific reports - 18 Jun 2020
Kang Hee-Ju, Park Yoomi, Yoo Kyung-Hun, Kim Ki-Tae, Kim Eun-Song, Kim Ju-Wan, Kim Sung-Wan, Shin Il-Seon, Yoon Jin-Sang, Kim Ju Han, Kim Jae-Min
Abstract excerpt
The prevalence and clinical characteristics of depressive disorders differ between women and men; however, the genetic contribution to sex differences in depressive disorders has not been elucidated. To evaluate sex-specific differences in the genetic architecture of depression, whole exome sequencing of samples from 1000 patients (70.7% female) with depressive disorder was conducted. Control data from healthy...
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