Article

Blood transcriptomics reveals a Parkinson’s disease signature and heterogeneous prodromal molecular profiles in isolated RBD

2026-07-02

Abstract excerpt

<h4>Background</h4> Parkinson’s disease (PD) has a prolonged prodromal phase, but minimally invasive molecular biomarkers distinguishing manifest PD from prodromal synucleinopathy remain insufficiently characterized. Isolated REM sleep behavior disorder (iRBD) represents a high-risk prodromal condition and provides an opportunity to investigate early blood-based transcriptional alterations. <h4>Objective</h4> To...

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Literature Corpus work: 491806fe-3417-5f18-9181-975cfc651682
DOI: 10.64898/2026.06.30.26356917

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